Investor Presentation - Capital Raising
Released
Released
Announcement PDF
ASX: RAD | NASDAQ: RADX
July 2026
A Multi-Asset Radiopharmaceutical
Platform
Capital Raising Presentation
Clinical-stage oncology radiopharmaceuticals — diagnostics and
therapeutics
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Notice & Disclaimer
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The information in this presentation does not constitute personal investment advice. The presentation is not intended to be comprehensive or provide all information required by investors to make an informed
decision on any investment in Radiopharm Theranostics Ltd ACN 647 877 889 (Company). In preparing this presentation, the Company did not take into account the investment objectives, financial situation
and particular needs of any particular investor. Further advice should be obtained from a professional investment adviser before taking any action on any information dealt with in the presentation. Those acting
upon any information without advice do so entirely at their own risk.
Whilst this presentation is based on information from sources which are considered reliable, no representation or warranty, express or implied, is made or given by or on behalf of the Company, any of its
directors, or any other person about the accuracy, completeness or fairness of the information or opinions contained in this presentation. No responsibility or liability is accepted by any of them for that
information or those opinions or for any errors, omissions, misstatements (negligent or otherwise) or for any communication written or otherwise, contained or referred to in this presentation. Neither the
Company nor any of its directors, officers, employees, advisers, associated persons or subsidiaries are liable for any direct, indirect or consequential loss or damage suffered by any person as a result of relying
upon any statement in this presentation or any document supplied with this presentation, or by any future communications in connection with those documents and all of those losses and damages are
expressly disclaimed.
Certain statements contained in this presentation, including, without limitation, statements containing the words “believes,” “plans,” “expects,” “anticipates,” and words of similar import, constitute “forward-
looking statements.” Such forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause the actual results, performance or achievements of the Company to be
materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. Such factors include, among others, the following: the risk that our clinical
trials will be delayed and not completed on a timely basis; the risk that the results from the clinical trials are not as favourable as we anticipate; the risk that our clinical trials will be more costly than anticipated;
and the risk that applicable regulatory authorities may ask for additional data, information or studies to be completed or provided prior to their approval of our products. Given these uncertainties, undue reliance
should not be placed on such forward-looking statements. The Company disclaims any obligation to update any such factors or to publicly announce the results of any revisions to any of the forward-looking
statements contained herein to reflect future events or developments except as required by law.
This presentation is not a prospectus or other disclosure document under the Corporations Act 2001 (Cth) and will not be lodged with the Australian Securities and Investments Commission. This presentation is
for information purposes only and is not an invitation or offer of securities for subscription, purchase or sale in any jurisdiction. The distribution of this presentation (including electronically) outside Australia is
restricted by law. If you come into possession of this presentation, you should observe such restrictions as any non- compliance with these restrictions could contravene applicable securities laws (see the
section captioned ‘International offer restrictions’). In particular, this document does not constitute an offer to sell, or a solicitation of an offer to buy, securities in the United States. The New Shares, Attaching
Options and shares underlying the Attaching Options have not been, and will not be, registered under the US Securities Act of 1933 and may not be offered or sold in the United States except in transactions
registered under the US Securities Act or in transactions exempt from, or not subject to, the registration requirements of the US Securities Act and applicable US state securities laws.
Any opinions expressed reflect the Company’s position at the date of this presentation and are subject to change.
INVESTMENT HIGHLIGHTS
A multi-asset radiopharmaceutical platform — a Phase III-ready imaging lead plus four clinical-stage therapeutics.
Clear path to Phase III
FDA Fast Track; registrational Phase
III ready to start Q4 2026.
RAD101 large unmet market
~300,000 US patients p.a.; potential
>US$500m US sales; no direct
competitor.
Established partners
Siemens Healthineers for Ph 3
distribution in USA;
Advanced Strategic discussions for
partnering; M&A company retained
Phase I: Efficacy at Dose
Level 3
First patient treated at 90mCi achieved
-43% tumor reduction;
Second patient treated shows a similar
positive trend
Funded through key
milestones
Pro-forma cash of A$28.5m1 (3 July
2026) post raise
RAD101 HIGHLIGHTS: POSITIVE PHASE 2b READOUT: ≥ 93% of the patients achieved the Primary Endpoint
RAD204 HIGHLIGHTS: CLINICAL EFFICACY, 1st patient dosed at 90 mCi reported sustained tumor reduction
RAD 204 very large market
First in class; no direct competitor
~USD10B total addressable market
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1A$12.5 million Placement and fully subscribed A$6.0 million SPP
Company Pipeline in Clinical Stage
First two programs reporting strong clinical data. Additional upside from the other three Phase I trials
PROGRAM INDICATION ISOTOPE PHASE I PHASE II PHASE III CATALYSTS
PD-L1+ solid tumors 177Lu
Clinical activity reported
July 2026
Dose-escalation completion
Q4 2026 – Q1 2027
HER2+ solid tumors 177Lu
Dose-escalation completion
H1 2027
RAD402 KLK3 (prostate cancer) 161Tb
Dose-escalation completion
H2 2027
RV01 B7-H3 (solid tumors) 177Lu
Dose-escalation completion
H2 2027
RAD101 Imaging — brain mets 18F
Positive Phase 2b read-out
July 2026
¹⁷⁷Lu, lutetium-177; ¹⁶¹Tb, terbium-161; ¹⁸F, fluorine-18; B7-H3, B7 homolog 3; HER2, human epidermal growth factor receptor 2; KLK3, kallikrein-3; PD-L1, programmed death ligand-1.
RAD202
RAD204
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One Phase IIb imaging lead (RAD101) and four Phase I therapeutics across validated oncology targets.
Pharma Partnership Window
KEY CATALYSTS & MILESTONES
Consistent clinical & regulatory delivery since mid-2025, with multiple value-driving catalysts approaching from mid-2026 into 2027
Achieved milestones sourced from Radiopharm Theranostics ASX and GlobeNewswire announcements (Jul 2025 - Apr 2026); upcoming timing reflects
management expectations and is indicative. Phase IIb topline readout (Jul 2026) not yet reported.
Achieved Milestones
Upcoming Milestones
RAD101 Phase IIb
1st interim: 92% MRI
concordance (11/12)
Dec 2025
RV-01
first patients dosed
(Phase 1/2a)
Feb 2026
RAD101 Phase IIb
2nd interim: 90% MRI
concordance (18/20)
Mar 2026
Siemens
Healthineers supply
pact for planned US
Phase III
Apr 2026
RAD101 Phase IIb
readout (final 30-
patient cohort)
Jul 2026
FDA Phase III
protocol
alignment
meeting
Sep 2026
RAD101
Phase III
registrational
trial starts
Q4 2026
Partnering /
monetisation
discussions
advance
Q4 2026 1H 2027
RAD204
Efficacy data
released
RAD402
first patients dosed
(Phase 1/2a)
Mar 2026
RAD204
Phase I
read out
RAD202
Phase I
read out
RAD202
Expected Efficacy
data released
Q4 2026
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RAD 101 DIAGNOSTIC
Imaging lead asset — RAD 101
First-in-class PET imaging agent for brain metastases
T H E A G E N T
FASN
Tumor target
Pivalate
Targeting molecule
¹⁸F
PET isotope
Short-chain fatty-acid analogue
Brain-metastasis indication
Fatty acid synthase (FASN) — a validated target
Targets the FASN fatty-acid metabolism pathway
Detects recurrence after stereotactic radiosurgery (SRS)
Addresses a major diagnostic gap in neuro-oncology
High unmet need in early relapse detection
FDA Fast Track Phase 2b Positive Read-out
First-in-class PET imaging for post-SRS brain-metastasis recurrence — no direct competitor.
FASN, fatty acid synthase; ¹⁸F, fluorine-18; PET, positron emission tomography; SRS, stereotactic radiosurgery.
RAD 101 DIAGNOSTIC
Imaging lead asset — RAD101
First-in-class PET tracer to advance to Phase 3 — near-term value and optionality
THE NEED
High unmet Need - SoC MRI falls short
Early identification of recurrent brain metastases is urgent need in
suspected relapse after SRS.
THE MARKET
300,000
~300,000 new brain-metastasis patients post-SRS each year (US) — with
no direct competitor in this imaging sector.
THE ASSET
First-in-class PET tracer
RAD101 (¹⁸F-pivalate) is a FASN-targeted PET tracer designed to close
this diagnostic gap.
THE DATA
Phase 3 preparation started
Company-sponsored Phase 2b (US, N=30); interim N=20 positive ·
Positive Phase IIb data
Islam S, et al. EJNMMI 2025. doi.org/10.1007/s00259-025-07118-0. FASN, fatty acid synthase; MRI, magnetic resonance imaging; PET, positron emission
tomography; SoC, standard of care; SRS, stereotactic radiosurgery; SUV, standardized uptake value. 7
RAD 101 DIAGNOSTIC
RAD101 Phase IIb — primary endpoint readout
Primary endpoint met — high concordance with MRI.
PRIMARY ENDPOINT
Concordance with MRI
SUCCESSFULLY ACHIEVED
≥ 93%
28* / 30 patients concordant
SECONDARY ENDPOINT · INTERIM ANALYSIS
SPECIFICITY PENDING
Not yet available
Read-out expected Q4 2026
Primary endpoint met — ≥ 93% concordance with MRI · full sensitivity and specificity read-out expected Q4 2026.
MRI, magnetic resonance imaging.
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SENSITIVITY INTERIM
≥ 86%
12 / 14 patients
*3/30 Patient data not yet available
RAD 101 DIAGNOSTIC
RAD101 - Next steps to Phase 3
A clear, de-risked path to a Phase 3 start in Q4 2026
MILESTONES
May 2026
Advisory Board
Supportive of Phase 3
Sep 2026
FDA protocol meeting
Align on trial design
Q4 2026
Phase 3 start
Ready to initiate
Trial design
N=150–200 patients · primary endpoints: sensitivity &
specificity
Supply & logistics
US radiolabeling & distribution outsourced to a global leader —
contract signed with Siemens PETNET
Partnering opportunity assessment — contract signed with a radiopharma specialist in M&A
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Partnering opportunity assessment
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RAD 101 DIAGNOSTIC
Structured partnering process underway with global radiopharma players.
Radiopharmaceuticals are an actively consolidating sector - over US$10bn of M&A and partnerships in recent years - as Radiopharm
advances a de-risked, multi-asset pipeline toward partnering.
Potential Partners
Global radiopharma-active pharma — illustrative universe
Process Status
– Specialist radiopharmaceutical M&A adviser engaged
– Initial meetings conducted; parties assessing the opportunity
– Further partner interactions underway
Recent Radiopharmaceutical Deals
Selected M&A and partnerships, 2017–2025
Bristol Myers Squibb / RayzeBio US$4.1bn · 2023
Novartis / Adv. Accelerator Apps US$3.9bn · 2017
Novartis / PeptiDream up to US$2.7bn · 2025
AstraZeneca / Fusion Pharma US$2.4bn · 2024
Novartis / Mariana Oncology up to US$1.75bn · 2024
Eli Lilly / Point Biopharma US$1.4bn · 2023
Eli Lilly / Aktis Oncology up to US$1.1bn · 2024
AstraZeneca / Nucleus RadioPharma Investment · 2025
POTENTIAL FIRST-IN-CLASS DIAGNOSTIC WITH COMMERCIAL SCALE
~300,000 patients/year (US), Potential >$500M annual sales (US)
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RAD 101 DIAGNOSTIC
Year
1
Year
2
Year
3
Year
4
Year
5
Year
6
Year
7
Year
8
Potential first-in-class diagnostic with
scalable adoption
Clear pathway to monetization through
partnering or commercialization
Comparables:
PYLARIFY (Lantheus) 12-month sales in US:
~970m
Illuccix (Telix) 12-month sales in US: ~700m
~300,000 US patients p.a.; >US$500m US sales potential vs Pylarify (~$970m) and Illucix (~$700m).
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RAD 101 DIAGNOSTIC
Why RAD101 will be adopted
Four reasons RAD101 fits — and wins — in post-treatment neuro-oncology imaging.
THE NEED
Clear unmet need
MRI is frequently equivocal in post-treatment brain metastases.
THE FIT
Fits existing workflow
PET is already standard — no new infrastructure required.
THE MOMENT
High-value decision point
Resolves the critical post-SRS recurrence question.
THE WHITE SPACE
No direct competitor
First-in-class PET agent for this indication.
Clear unmet need · fits existing PET workflow · high-value decision point · no direct competitor.
MRI, magnetic resonance imaging; PET, positron emission tomography; SRS, stereotactic radiosurgery.
RAD 204 THERAPEUTIC
RAD204 — First-in-class PD-L1 targeted radiotherapy
Validated immuno-oncology target
First-in-class PD-L1 targeted 177Lu radiotherapy
POTENTIAL POSITIONING
LEAD INDICATION
Post-IO NSCLC
High unmet-need setting after immunotherapy
EXPANSION
Multiple solid tumors
Across PD-L1–expressing tumor types
Expands a proven IO target into a new therapeutic modality
IO, immuno-oncology; NSCLC, non-small cell lung cancer; PD-L1, programmed death ligand-1; 177Lu, lutetium-177.
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RAD 204 THERAPEUTIC
RAD204: early efficacy signal
First patient dosed at Cohort 3 (90 mCi) — dose escalation ongoing under a Bayesian (BOIN) design
TRIAL DESIGN
PRIMARY OBJECTIVES
• Safety & tolerability of ¹⁷⁷Lu-RAD204
• Recommended Phase 2 dose
STUDY DESIGN
• BOIN dose-finding design
• Population: prior PD-L1+ (>1%)
metastatic disease
Phase I — Treatment (dose escalation)
30 mCi
1.1 GBq
DL1
Completed · 3 pts
60 mCi
2.2 GBq
DL2
Completed · 3 pts
90 mCi
3.3 GBq
DL3
2/3 recruited
120 mCi (tbd)
4.4 GBq
DL4
Planned
DL1–DL2: Tumor uptake confirmed; favorable safety profile, no DLT. DL3: Early clinical signal (see next slide).
BOIN, Bayesian optimal interval; DL, dose level; GBq, gigabecquerel; mCi, millicurie; PD-L1, programmed death ligand-1; tbd, to be determined. 14
RAD 204 THERAPEUTIC
RAD204: early clinical activity
First patient at 90 mCi achieved a confirmed RECIST Partial Response with durable (7+ months) tumor shrinkage
Partial Response
RECIST Confirmed (Pt #7)
7+ months PFS
No evidence of progression
DOSE LEVEL #3 · 90 mCi (3.3 GBq) · NSCLC
Patient #7 NSCLC · No DLT PARTIAL RESPONSE
Safety No DLT
Kidney dose* 8.1 Gy (cumulative,
4 doses)
PFS
7+ months,
no progression
Completed 4 doses.
Tumor shrinkage by cycle (dose)
-19%
D1
-43%
D2
-43%
D3
-35%
D4
*FDA guidance = 23 Gy (under discussion).
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Patient #8 NSCLC · No DLT STABLE DISEASE
Safety No DLT
Kidney dose* 0.9 Gy (Dose 1)
PFS
2+ months,
no progression
Only 1 dose received, continuing to next dose
Tumor shrinkage by cycle (dose)
-7%
D1
2+ months PFS
No evidence of progression
Stable disease
Positive trend in tumor reduction (Pt #8)
RAD 204 THERAPEUTIC
Baseline
October ‘25
1st dose
November ‘25
2nd dose
January ‘26
3rd dose
March ‘26
Patient #7 — first patient treated at 90 mCi
Durable confirmed RECIST partial response across multiple cycles
NSCLC — progressed after multiple prior therapies
• External-beam radiotherapy
• Chemotherapy (carboplatin, taxane)
• PD-L1 checkpoint inhibitor
Expected PFS
4–6 months
Treated with RAD204 at 90 mCi
Confirmed RECIST PR 43% tumor-size reduction PFS 7 months & ongoing
SPECT/CT — Complete Response
RLL primary at IM, C1–C3
SUVmax
2.71 → 1.14 → 0.93 → 0 / nd
CORONAL CT · RLL PRIMARY
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RAD204 Investment Case
RAD 204 THERAPEUTIC
PD-L1 is the largest and most validated
immuno-oncology target
Targeted radiotherapy introduces a new
principle combining two synergistic
mechanisms of action
Addressable market (US, post-IO NSCLC)
40,000–65,000
patients per year
Platform enables continued optimization
across the pipeline
Early clinical signal already observed at
dose level #3
First-in-class: no radiopharma competitors
identified
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RAD 202 THERAPEUTIC
Phase I dose escalation with a favorable safety profile
First two cohorts completed with no DLTs — Dose Level 3 dosed at 130 mCi
TRIAL DESIGN
PRIMARY OBJECTIVES (PHASE 1)
• Safety & tolerability of ¹⁷⁷Lu-RAD202
• Recommended Phase 2 dose
POPULATION
• HER2+ (IHC, ISH) advanced or
metastatic solid tumors
Phase I — Treatment (dose escalation)
30 mCi
1.1 GBq
DL1
Completed · 3 pts
75 mCi
2.7 GBq
DL2
Completed · 3 pts
130 mCi
4.8 GBq
DL3
Cohort 3 dosed
3/3 recruited
200 mCi (tbd)
7.4 GBq
DL4
Planned
DL1–DL2: Tumor uptake confirmed; favorable safety, no DLT. DL3: Clinical activity under assessment.
a/m, advanced or metastatic; DL, dose level; DLT, dose-limiting toxicity; GBq, gigabecquerel; HER2, human epidermal growth
factor receptor 2; IHC, immunohistochemistry; ISH, in situ hybridization; mCi, millicurie; TBD, to be determined. 18
RAD 202 THERAPEUTIC
RAD202: Cohort #3 expected to complete by September
Evidence of tumor radiation at Dose Level 3 (130 mCi)
Completing by September
3 patients dosed in Cohort #3
No DLT to date
Safety assessment ongoing
Next dose: 200 mCi
Escalation planned
DOSE LEVEL 3 · 130 mCi (4.8 GBq)
#8 Patient #8
Colorectal
PD
Safety No DLT
Kidney (at risk) 10 Gy · avg 2 doses
Tumor uptake 2.4 Gy · avg 2 doses
RECIST —
Stable disease 3 mo (dose 1+2); progressive disease
before 3rd dose.
#9 Patient #9
Breast
ONGOING, SD
Safety Assessment ongoing
Kidney (at risk) 11 Gy · 1 dose
Tumor uptake 9.8 Gy · 1 dose
RECIST Stable Disease
Unchanged after 1st dose; continuing to Dose 2 (Jul 14).
#10 Patient #10
Breast
ONGOING
Safety Assessment ongoing
Kidney (at risk) 8.9 Gy*
Tumor uptake 15 Gy*
RECIST —
Continuing to Dose 2 (Aug 4).
High uptake of the drug in the patients
DLT, dose-limiting toxicity; Gy, gray; mCi, millicurie; RECIST, Response Evaluation Criteria in Solid Tumours
* Preliminary values, calculated from normalized imaging dose.
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!
SUMMARY
A multi-asset radiopharmaceutical platform — a Phase III-ready imaging lead plus four clinical-stage therapeutics.
RAD 101
Successful Phase 2b trial in Brain
Mets
Advancing to single registrational
Phase 3
No Competition
Attractive asset for M&A
PIPELINE UPSIDE
RAD 202 has very promising
tumor uptake
RAD 402 & RV01 trials are
enrolling fast, with read-out in
2027
No dose-limiting toxicities
reported
RAD 204
Strong signal of Clinical Efficacy
reported in Phase I, Dose Level 3
No dose-limiting toxicity reported
No Competitor identified
Very Large total addressable
market
2026 CATALYSTS 2027 CATALYSTS
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BOARD & MANAGEMENT
Leadership with hands-on, successful development and commercial track record
Direct blockbuster radiopharmaceutical pedigree: Novartis / AAA (Lutathera, Lu-PSMA-617), Siemens PETNET and ANSTO — operators who have built
and commercialised the assets that define the sector.
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Riccardo Canevari
Chief Executive Officer
• Radiopharm Theranostics CEO since
September 2021
• Previously, Chief Commercial Officer of
Novartis Company Advanced Accelerator
Applications S.A.
• Lead for Lutathera in-market growth
strategy & Pluvicto launch strategy
• Senior Vice President & Global Head,
Breast Cancer Franchise, for Novartis
Oncology since 2017
• Founder of Radiopharm Theranostics
• 25 years experience as a life sciences
entrepreneur
• Founder, Chairman, non-executive director
or CEO of more than fifteen companies in
the US, Australia and Asia
• Previous and current Boards include
Imugene, Chimeric Therapeutics, Viralytics,
Prescient Therapeutics, Polynoma and
Arovella Therapeutics
Paul Hopper
Executive Chairman
Dr. Dimitris Voliotis
Chief Medical Officer
• Over 20 years experience in
pharmaceutical and biotechnology
sectors across US and Europe, with an
emphasis on radiopharmaceuticals
• Dr Voliotis has designed and executed
multiple registrational trials in numerous
oncology indications, multiple INDs,
preclinical through to first in human trials
and has overseen numerous regulatory
submissions
• Previously, Senior Vice President, Head
of Clinical Development at Convergent
Therapeutics
Dr. Ken Herrmann
Scientific Advisory Board
• Over 18 years of experience in
radioligand therapy and early clinical
translation of novel radioligand therapy
concepts
• Dr Herrmann currently serves as Chair
of the Department of Nuclear Medicine
at Universitätsmedizin Essen, Germany
• Experienced across translating
theranostics, ranging from first in
human use to contributing to pivotal
regulatory approval receiving phase 3
studies
Dr. Oliver Sartor
Scientific Advisory Board
• Dr Sartor is an internationally recognised
medical oncologist and scientist specialising in
prostate cancer and radiopharmaceutical
therapies
• Currently serves as Director of
Radiopharmaceutical Clinical Trials and Chair
of the Genitourinary Cancer Disease Group at
the world-renowned Mayo Clinic, in Rochester,
Minnesota.
• Since 1990, he has focused on prostate cancer
clinical research, authoring more than 500
peer-reviewed publications and leading
multiple pivotal Phase 3 trials that resulted in
FDA approvals.
LEADERSHIP TEAM SCIENTIFIC ADVISORY BOARD
CAPITAL RAISING
Offer details · Use of funds · Indicative timetable
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CAPITAL RAISING OVERVIEW
The Company is raising ~A$18.5 million1 via a Placement, US Direct Registration Offering & SPP
• A two-tranche Placement of fully paid ordinary shares (“New Shares”) to sophisticated and professional investors of ~A$6.7m (before costs)(“Placement”) comprising of:
o Tranche 1 Placement to raise ~A$6.1 million (before costs) through the issuance of ~408.8 million New Shares utilising the Company’s available placement capacity under ASX Listing
Rule 7.1 and 7.1A (“Tranche 1 Placement”); and
o Tranche 2 Placement to raise ~A$0.6 million (before costs) through the issuance of ~40.0 million New Shares, subject to shareholder approval at an Extraordinary General Meeting
(“EGM”) to be held on or around Friday, 11 September 2026 (“Tranche 2 Placement”).
Placement
• A current direct SEC-registered offering in the United States to raise ~US$4.1 million (~A$5.8 million) through the issuance of ~1.3 million American Depositary Shares (“ADS”) representing ~384.5
million fully paid ordinary shares at US$3.16 per ADS (“US Direct Registration Offering”).
US Direct
Registration
Offering
• A Share Purchase Plan to eligible shareholders raising approximately A$6.0 million2 (“SPP”). Eligible shareholders will be entitled to subscribe for up to A$100,000 of fully paid ordinary shares.
The issue of shares under the SPP is subject to shareholder approval at an Extraordinary General Meeting (“EGM”) to be held on or around Friday, 11 September 2026.
o The company has received commitments from investor to subscribe for up to A$3.0m in SPP shortfall commitments3.
Share Purchase
Plan
• The Placement will be offered at a price of A$0.015 per New Share (“Placement Offer Price”), which represents a:
o 21.1% discount to the last close price of A$0.019 as of Tuesday, 21 July 2026;
o 22.3% discount to the 5-day volume weighted average price (“VWAP”); and
• The SPP offer price (“SPP Offer Price”) will be the lower of:
o A$0.015 equal to the Placement Offer Price; or
o A 2.5% discount to the VWAP of shares traded on the ASX during the five trading days up to the closing date of the SPP, rounded to the nearest 0.1 cent.
Placement & SPP
Offer Price
• Participants in the Placement and SPP will receive one (1) free option (“Attaching Options”) for every one (1) New Share subscribed for under the Placement and SPP. Subject to satisfying
spread requirements set out in ASX Listing Rule 2.5, condition 6, the Attaching Options are intended to be quoted on the ASX with an exercise price of A$0.018 (20% premium to the Offer
Price) and an expiry date of 31 July 2029.
• Attaching Options issued under the Placement are subject to shareholder approval at an EGM of the Company to be held on or around Friday, 11 September 2026
Attaching Options
• Participants in the US Direct Registration Offering will subject to shareholder approval, receive one (1) warrant to purchase one (1) ADS (“ADR Warrant”) for every ADS subscribed for under the
US Direct Registration Offering.
• Each ADR will have an exercise price of US$3.79 per ADS, expiring 31 July 2029. The ADR will not be quoted on the ASX
ADR Warrant
• All new shares issued under the Placement and SPP will rank equally with existing RAD shares from the date of issue
Ranking
• Bell Potter Securities Limited (“Bell Potter”) are acting as Lead Manager and Bookrunner to the Placement & SPP
Lead Manager
• H.C. Wainwright & Co., LLC (“Wainwright”)
US Placement
Agent
1 Assumes a fully subscribed A$6m SPP
2The Company reserves the right to accept oversubscriptions under the SPP up to an additional A$4.0 million
3Investors providing SPP shortfall commitments will be issued an aggregate of 200,000,000 options on the same terms as the Attaching Options, subject to shareholder approval
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USE OF FUNDS
Capital raising proceeds will fund its commencement of the RAD101 registrational study while progressing multiple therapeutic programs
through key clinical milestones and supporting ongoing strategic partnering initiatives
A$M
SOURCE OF FUNDS
$10m
Existing Cash Balance1
$18.5m
Capital Raising2
$28.5m
TOTAL
1As of 3 July 2026
2A$12.5 million Placement & and fully subscribed A$6.0 million SPP
A$M
CAPITAL RAISE USE OF FUNDS
Drug Manufacturing
$5.7m
CMC GMP production for RAD 204 & RAD 202(new batches for
Phase II); CMC GMP production for RAD 402; RV01 (new
batches for Phase II)
CMC GMP production for RAD 101 (new batches for Phase III)
Clinical Trials
$13.3m
Phase 1 RAD 204, RAD 202, RV01, RAD 402
Phase 3 initiation for RAD 101
Administration, Working Capital and Offer Costs
$9.5m
General working capital, corporate costs, and offer costs
$28.5m
TOTAL
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INDICATIVE TIMETABLE
Key dates for the proposed offer - indicative only and subject to change
Date (Sydney Time)2
Indicative capital raising timetable1
Wednesday, 22 July 2026
Trading Halt
Wednesday, 22 July 2026
Placement Bookbuild Opens
7:00pm (AEST) Thursday, 23 July 2026
Record Date for SPP (7:00pm AEST)
Friday, 24 July 2026
Capital raising announced, and trading halt lifted
Friday, 31 July 2026
Settlement of Placement Shares
Monday, 3 August 2026
Allotment of Placement Shares
Friday, 7 August 2026
SPP Opens
Thursday, 10 September 2026
SPP Closes
Expected on or around Friday, 11 September 2026
EGM to approve New Shares under Tranche 2 of the Placement, SPP Offer and Attaching Options
Expected on or around Tuesday, 15 September 2026
Announce results of SPP
Expected on or around Wednesday, 16 September 2026
Settlement of New Shares issued under the Tranche 2 Placement, SPP Offer and Attaching Options
Expected on or around Thursday, 17 September 2026
Allotment of New Shares issued under the Tranche 2 Placement, SPP Offer and Attaching Options
1 The timetable is indicative only and subject to change by the Company and Lead Manager, subject to the Corporations Act and other applicable laws
2 All times are expressed in Australian Eastern Standard Time (AEST) unless otherwise indicated
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KEY RISKS
Radiopharm’s ability to achieve profitability is dependent on a number of factors, including its ability to complete successful clinical
trials, obtain regulatory approval for its products and successfully commercialise those products. There is no guarantee that
Radiopharm’s products will be commercially successful.
Pipeline product in
development and not
approved for commercial
sale
Radiopharm may be unable to secure necessary approvals from regulatory agencies and institutional bodies (clinics and hospitals) to
conduct future clinical trials. There is also no assurance that products developed using Radiopharm’s technology will prove to be safe
and efficacious in clinical trials, or that the regulatory approval to manufacture and market its products will be received. Clinical trials
might also potentially expose Radiopharm to product liability claims in the event its products in development have unexpected effects
on clinical subjects. Unsuccessful clinical trial results could have a significant impact on the value of Radiopharm’s securities and the
future commercial development of its technologies.
Clinical trial risk
The research, development, manufacture, marketing and sale of products using Radiopharm’s technology are subject to varying
degrees of regulation by a number of government authorities in Australia and overseas. Products may also be submitted for
reimbursement approval. The availability and timing of that approval may have an impact upon the uptake and profitability of
products in some jurisdictions.
Regulatory and
reimbursement approvals
Radiopharm has not yet commercialised its technology and as yet has no material revenues.
Commercialisation of
products and potential
market failure
Radiopharm depends on the talent and experience of its personnel as its primary asset. There may be a negative impact on
Radiopharm if any of its key personnel leave.
Dependence upon key
personnel
26
KEY RISKS (CONT.)
Radiopharm may pursue collaborative arrangements with pharmaceutical and life science companies, academic institutions or other
partners to complete the development and commercialisation of its products. There is no assurance that Radiopharm will attract and
retain appropriate strategic partners or that any such collaborators will perform and meet commercialisation goals. If Radiopharm is
unable to find a partner, it would be required to develop and commercialise potential products at its own expense. This may place
significant demands on the Company’s internal resources and potentially delay the commercialisation of its products.
Arrangements with third-
party collaborators
Radiopharm may experience delay in achieving a number of critical milestones, including securing commercial partners, completion of
clinical trials, obtaining regulatory approvals, manufacturing, product launch and sales. Any material delays may impact adversely
upon the Company, including the timing of any revenues under milestone or sales payments.
Risk of delay and
continuity of
operations
The biotechnolog
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